Peptides like BPC-157, TB-500, CJC-1295 and retatrutide are among the hottest trends for optimizers, gym bros, looksmaxxers and the longevity crowd. But is it wise to inject bioactive molecules into the bloodstream that haven’t passed the drug-approval process?
In this episode, Marty and Stu welcome the Harvard- and Stanford-educated Leigh Baxt, who mythbusts about peptides and other panaceas on Instagram @sciencemomscicomm.
Baxt is a translational scientist who specializes in drug development. She points out the many problems with injecting peptides into the body, including the major one that many of these peptides are activating biological pathways that cancer cells love.
In this episode we discuss the following questions:
What are peptides?
Are peptides safe?
Quick guide to peptides like BPC-157, TB-500, CJC-1295 and retatrutide
What do peptides do?
What is a wolverine stack?
Finally, we also walk through the drug-approval process that protects human beings from predatory marketing, and say what Marty, Stu and Leigh think is so wrong about promoting peptides to young people.
What scientific evidence supports peptide use? Find the answer in our latest episode!
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EPISODE LINKS
Leigh Baxt is on Instagram @sciencemomscicomm
Leigh collaborates heavily with Unbiased Science: https://www.unbiasedscience.com/
Leigh was also on Simon Hill: Are Peptides Safe? What You Need to Know About BPC-157
Retatrutide phase 2 trial for obesity in the New England Journal of Medicine
Good overview from Patricia Brubaker on problems with injecting peptides
Want to hack your body with peptides? The Economist opines
SHOW LINKS
Follow or subscribe at your favourite platform @realexercisescience: Substack. YouTube. TikTok. Instagram. Apple Podcasts. Spotify. On X you can find us @realexscience.
Stu is everywhere, too, but mostly on Instagram and X. Follow him on TikTok too!
Marty just started his own Instagram. Give him a follow! He’s also on X!
Exercise Science is produced by Ghost Bureau, the Toronto content agency.
DISCUSSION POINTS
00:00 Cold open
01:02 Introducing Leigh Baxt
04:54 What are peptides?
07:25 Antivaxxers
09:24 BPC-157
11:05 TB-500
12:20 Wolverine stacking
13:10 CJC-1295
13:55 Retatrutide
16:28 Drug approval process
18:08 Peptides & cancer
20:12 Most drugs fail
22:03 Are peptides safe
23:52 Peptides & patents
26:28 Peptide categories
27:35 What’s wrong with wolverine stacks
29:54 Drug interactions
31:53 Why are peptides so hot?
34:27 Predatory marketing
37:21 Peptide predictions
DISCLAIMER
The Exercise Science podcast is for educational and entertainment purposes only and is not a substitute for professional medical advice. Strength training and fitness carry inherent risks. Always consult with a physician or qualified healthcare provider before starting any new exercise program or making changes to your diet. The hosts, producers, sponsors and guests of this podcast disclaim any liability for any injuries or losses connected with the information discussed in this show.
The science of strength and fitness is continually evolving. While we strive to provide accurate, evidence-based information, we make no representations or warranties regarding the completeness, accuracy, or timeliness of the information discussed.
Martin Gibala is an advisor to and holds equity in Longevity League Ltd., a US-based company whose services in part relate to exercise.
Leigh Baxt does not represent her employer on this platform and all views expressed are her own.
